Nicholas Van Panhuys PhD
Principal Investigator – Assistant Level Asthma and Allergy Laboratory
Email: nvanpanhuys (@) sidra.org
SELECTED PUBLICATIONS(†equal contribution, *corresponding):
- Liarski VM, Sibley A, van Panhuys N, Ai J, Chang A, Kennedy D, Merolle M, Germain RN, Giger ML, Clark MR. Quantifying in situ adaptive immune cell cognate interactions in humans. Nat Immunol. (2019)
- Abbirami Sathappan and Nicholas van Panhuys* Advances in In Vivo Imaging Techniques for the Visualization and Quantification of DC-T Cell Interactions. Journal of Immunobiology. (2017)
- Van Panhuys, N*. Studying Dendritic Cell-T Cell Interactions Under In Vivo Conditions. Methods in Molecular Biology. (2017)
- Veres T, Kopcsányi T, van Panhuys N, Gerner M, Liu Z, Rantakari P,Dunkel J, Miyasaka M, Jalkanen S, Germain R. CD4+ T-cell cytokine production within airway mucosal DC-T-cell clusters drives the local recruitment of myeloid effector cells in response to house dust mite allergen. Journal of Immunology. (2017)
- Van Panhuys, N. TCR signal strength alters T-DC activation and interaction times and directs the outcome of differentiation. Frontiers in Immunology.(2016)
- Liu Z, Gerner MY, Van Panhuys N, Levine AG, Rudensky AY, Germain RN. Immune homeostasis enforced by co-localized effector and regulatory T cells. Nature. (2015)
- Palmer DC, Guittard GC, Franco Z, Crompton JG, Eil RL, Patel SJ, Ji Y, Van Panhuys N, Klebanoff CA, Sukumar M, Clever D, Chichura A, Roychoudhuri R, Varma R, Wang E, Gattinoni L, Marincola FM, Balagopalan L, Samelson LE, Restifo NP. Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance. J Exp Med. (2015)
- Chong WP, van Panhuys N, Chen J, Silver PB, Jittayasothorn Y, Mattapallil MJ, Germain RN, Caspi RR. NK-DC crosstalk controls the autopathogenic Th17 response through an innate IFN-γ-IL-27 axis. J Exp Med. (2015)
- Kolodin D, van Panhuys N, Li C, Magnuson AM, Cipolletta D, Miller CM, Wagers A, Germain RN, Benoist C, Mathis D. Antigen- and cytokine-driven accumulation of regulatory T cells in visceral adipose tissue of lean mice. Cell Metab. (2015)
- van Panhuys N, Klauschen, F and Germain, R. T Cell Receptor-dependent Signal Intensity Dominantly Controls CD4+ T Cell Polarization In Vivo. Immunity. (2014)