Cristina Maccalli, PhD

Principal Investigator – Assistant Level Laboratory of Immune Biological Therapy

Email: cmaccalli (@)

SELECTED PUBLICATIONS(equal contribution, *corresponding):

  • Maccalli C*, Rasul K, Elawad M, Ferrone S. The role of cancer stem cells in the modulation of anti-tumor immune responses. Semin Cancer Biol (2018), 153:189-200.
  • Pilla L, Ferrone S, Maccalli C*. Methods for improving the immunogenicity and efficacy of cancer vaccines. Expert Opin Biol Ther (2018), 18:765-784.
  • Pilla L, Maccalli C*. Immune Profiling of Cancer Patients Treated with Immunotherapy: Advances and Challenges. Biomedicines (2018) 6: pii: E76.
  • MennonnaD#, MaccalliC#, RomanoMC, CapocefaloF, BordoniR, De BellisG, SidneyJ, SetteA, GoriA, LonghiR, GhirardelliL, BaldariL, OrsenigoE, BragaM, AlbarelloL, ZinoE, FleischhauerK, MazzolaG, FerreroN, AmorosoA, CasoratiG, ParmianiG, DellabonaP. T cell-neoantigens of colorectal cancer identified by high throughput profiling of somatic mutations in expressed genes. Gut (2017) 66:454-463.
  • Maccalli C*, Giannarelli D, Chiarucci C, Cutaia C, Giacobini G, Hendricx W, Amato G, Annesi D, Bedognetti D, Altomonte M, Danieli R, Calabro’ L, Di Giacomo AM, Marincola FM, Parmiani G, Maio M. Soluble NKG2D ligands are biomarkers associated with the clinical outcome to immune checkpoint blockade therapy of metastatic melanoma patients. OncoImmunol (2017) 6:e1323618.
  • Maccalli C*, Parmiani G, Ferrone S. Immunomodulating and immunoresistance properties of cancer initiating cells: implications for the clinical success of immunotherapy. Immunol Invest (2017) 46:221-238.
  • Gulley JL, Berzofsky JA, Butler MO, Cesano A, Fox BA, Gnjatic S, Janetzki S, Kalavar S, Karanikas V, Khleif SN, Kirsch I, Lee PP, Maccalli C, Maecker H, Schlom J, Seliger B, Siebert S, Stroncek DF, Thurin M, Yuan J, Butterfield LH. Immunotherapy Biomarkers 2016: Overcoming the Barriers. J Immunother Cancer (2017), 5:29.
  • Roelands J, Kuppen P.JK, Vermeulen L, Maccalli C, Decock J, Wang E, Marincola FM, Bedognetti D, Hendrickx W. Immunogenomic classification of colorectal cancer and therapeutic implications. Int J Molecular Science 2017, 18:pii: E2229.
  • Hendrickx W, Simeone I, Anjum S, Mokrab Y, Bertucci F, Finetti P, Curigliano G, Seliger B, Cerulo L, Tomei S, Delogu LG, Maccalli C, Wang E, Miller LD, Marincola FM, Ceccarelli M, Bedognetti D. Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis. OncoImmunol (2016) 6:e1253654.
  • Yuan J, Hegde PS, Clynes R, Foukas PG, Harari A, Kleen TO, Kvistborg P, Maccalli C, Maecker HT, Page DB, Robins H, Song W, Stack EC, Wang E, Whiteside TL, Zhao Y, Zwierzina H, Butterfield LH, Fox BA. Novel technologies and emerging biomarkers for personalized cancer immunotherapy. J Immunother Cancer (2016) 4: 3-28.