Davide Bedognetti, PhD

Director – Cancer Program Principal Investigator – Full Level Cancer Immunogenetics Laboratory

Email: dbedognetti (@) sidra.org

SELECTED PUBLICATIONS(equal contribution, *corresponding):

  • Roelands J, Hendrickx W, Kuppen P, Mall R, Zoppoli G, Saad M, Halliwill K, Curigliano G, Rinchai D, Decock J, Delogu LG, Turan T, Samayoa J, Chouchane L, Wang E, Finetti P, Bertucci F, Miller LD, Galon J, Marincola FM, Ceccarelli M, Bedognetti D*. Oncogenic states dictate the prognostic and predictive connotations of intratumoral immune respons. J Immunother Cancer (2019, to appear)
  • Bedognetti D, Ceccarelli M, Galluzzi L, Lu R, Palucka K, Samayoa J, Spranger S, Warren S, Wong KK, Ziv E, Chowell D, Coussens LM, De Carvalho DD, DeNardo DG, Galon J, Kaufman HL, Kirchhoff T, Lotze MT, Luke JJ, Minn AJ, Politi K, Shultz LD, Simon R, Thórsson V, Weidhaas JB, Ascierto ML, Ascierto PA, Barnes JM, Barsan V, Bommareddy PK, Bot A, Church SE, Ciliberto G, De Maria A, Draganov D, Ho WS, McGee HM, Monette A, Murphy JF, Nisticò P, Park W, Patel M, Quigley M, Radvanyi L, Raftopoulos H, Rudqvist NP, Snyder A, Sweis RF, Valpione S, Butterfield LH, Disis ML, Fox BA, Cesano A, Marincola FM; Society for Immunotherapy of Cancer (SITC) Cancer Immune Responsiveness Task Force and Working Groups. Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop. J Immunother Cancer (2019)7(1)
  • Thorsson V, Gibbs DL, Brown SD, Wolf D, Bortone DS, Ou Yang TH, Porta-Pardo E, Gao GF, Plaisier CL, Eddy JA, Ziv E, Culhane AC, Paull EO, Sivakumar IKA, Gentles AJ, Malhotra R, Farshidfar F, Colaprico A, Parker JS, Mose LE, Vo NS, Liu J, Liu Y, Rader J, Dhankani V, Reynolds SM, Bowlby R, Califano A, Cherniack AD, Anastassiou D, Bedognetti D, Mokrab Y, Newman AM, Rao A, Chen K, Krasnitz A, Hu H, Malta TM, Noushmehr H, Pedamallu CS, Bullman S, Ojesina AI, Lamb A, Zhou W, Shen H, Choueiri TK, Weinstein JN, Guinney J, Saltz J, Holt RA, Rabkin CS; Cancer Genome Atlas Research Network, Lazar AJ, Serody JS, Demicco EG, Disis ML, Vincent BG, Shmulevich I. Immunity (2018) 51(2):411-412.
  • Rozenblit M, Hendrickx W, Heguy A, Chiriboga L, Loomis L, Ray K, Darvishian F, Egeblad M, Demaria S, Marincola M, Bedognetti D*, Adams S*. Transcriptomic profiles conducive to immune-mediated tumor rejection in human breast cancer skin metastases treated with Imiquimod.Sci Rep(2019)9(1):8572.
  • Angelova M, Mlecnik M, Vasaturo A, Bindea G, Fredriksen T , Lafontaine L , Buttard B , Morgand E , Bruni D, Jouret-Mourin A , Hubert C , Kartheuser A, Humblet Y , Ceccarelli M , Syed N, Marincola FM, Bedognetti D, Van den Eynde M, Galon J. Evolution of Tumor Metastases in Space and Time under Immune Selection. Cell (2018)175:1-15.
  • Bertucci B, Finetti P, Simeone I, Hendrickx W, Wang E, Marincola F, Viens P, Mamessier E, Ceccarelli M, Birnbaum D, Bedognetti D. The Immunologic Constant of Rejection classification (ICR) refines the prognostic value of conventional prognostic signatures in breast cancer. Br J Cancer (2018) 19(11):1383-1391.
  • Orecchioni M, Bedognetti D, Newman L, Fuoco C, Spada F, Hendrickx W,Marincola FM,Sgarrella F,Rodrigues FA, Ménard-Moyon C,Cesareni G,Kostarelos K,Bianco, Delogu LG. Single-cell mass cytometry and transcriptome profiling reveal the impact of graphene nanomaterials on human immune cells. Nat Commun (2017)8(1): 1109.
  • HendrickxW, Simeone I, AnjumS, MokrabY, Bertucci F, Finetti P, CuriglianoG, SeligerB, CeruloL, Tomei S, DeloguLG, MaccalliC, WangE, MillerLD, MarincolaFM, CeccarelliM, BedognettiD*. ­Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis. Oncoimmunology (2017)6(2):e1253654.
  • Roelands J, Decock J, Boughorbel S, Rinchai D, Maccalli C, Ceccarelli M, Black M, Print C, Chou J, Presnell S, Quinn C, Jithesh P, Syed N, Al Bader S, Wang E, Marincola FM, Chaussabel D, Kuppen P, Miller L, BedognettiD*, Hendrickx W. A collection of annotated and harmonized human breast cancer gene expression datasets including immunologic classification.F1000Research (2017)6:296.
  • Cocca, M, Bedognetti, D, La Bianca, M, Gasparini, P, Girotto, G: Pharmacogenetics driving personalized medicine: analysis of genetic polymorphisms related to breast cancer medications in Italian isolated populations. J Transl Med (2016) 14:22.