Chiara Cugno, MD
Director - Advanced Cell Therapy Core
Advanced Cell Therapy Core
- Email: ccugno (@) sidra.org
- Phone: +974 7478 2930
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Dr. Cugno joined Sidra in 2014, where she covers the double role of Director of the Advanced Cell Therapy Core and Attending Physician in Pediatric Oncology and Hematology.
She is a 20-year experienced medical doctor with a Board Certification in Pediatrics and Pediatric Hematology/Oncology at the University of Pavia (Italy), and a Master in Pediatric Hematology at the University “La Sapienza”, Rome (Italy).
In Italy, she has been directly involved in the Hematopoietic Stem Cell Transplantation (HSCT) activities at the Pediatric Hematology/Oncology Unit, Fondazione IRCCS Policlinico San Matteo, a renowned Academic Health Center that has performed more than 2000 transplantations.
At Sidra, Dr. Cugno has been working on the development of the Advanced Cell Therapy Core, including a Cellular Therapy Unit for the delivery of cellular products for tissue, cell and gene therapy, and a Clinical Trial Office.
Activities currently range from Hematopoietic Stem Cells processing, as part of the Bone Marrow Transplantation clinical program, to several projects of cell therapy (i.e. production of mesenchymal stromal cell from different sources), gene therapy (i.e. gene therapy approaches in Hemophilia) and regenerative medicine (i.e. production of platelet rich plasma, platelet rich fibrin, adipose-derived stem cells and cell-drug codelivery).
- Mesenchymal Stromal Cells
- Pediatric leukemia (Omics and pharmacogenomics)
- Inherited Bone Marrow Failure Syndromes (genetic and epigenetic make-up)
- Graft-versus-host disease
- Manufacturing of Cell, CAR-T and Gene Therapies
- Regenerative and Engineering Medicine
- Quality, GxP and Good Manufacturing Practice
Clinical Services
Massimino Miele, BSc
Manager – Advanced Cell Therapy Core Laboratories
Email: mmiele (@) sidra.org
Che-Ann Lachica, MScMLS
Lab Technologist, Research Specialist II
Email: clachica@sidra.org
Sheanna M. Herrera, MPH
Lab Technologist, Research Specialist I
Email: sherrera@sidra.org
R&D BMT, Cell and Gene Therapy
Sara Deola, MD, PhD
Investigator, Cell and Gene Therapy Specialist
Email: sdeola@sidra.org
Dhanya Kizhakayil, PhD
Post-Doctoral Fellow
Email: dkizhakayil@sidra.org
Anjud Al Mohannadi, MSc
Research Specialist I
Email: aalmohannadi2@sidra.org
Aesha Ali, PhD
Research Specialist I
Email: aali11 (@)sidra.org
Clinical Trial Office
Christine Solfelix, BSc, CPM
Clinical Protocol Manager
Email: csolfelix@sidra.org
Mohammed Elanbari, PhD
Staff Scientist – Biostatistics
Email: melanbari@sidra.org
Blessing Dason, MSN
Research Nurse
Email: bdason@sidra.org
Selected publications (†co-first, *corresponding):
- Cugno C, Kizhakayil D et al. Omega-3 fatty acid-rich fish oil supplementation prevents rosiglitazone-induced osteopenia in aging C57BL/6 mice and in vitro studies. Sci Rep. 2021 May 14;11(1):10364.
- Maacha S, Sidahmed H, Jacob S, Gentilcore G, Calzone R, Grivel JC, Cugno C. Paracrine Mechanisms of Mesenchymal Stromal Cells in Angiogenesis. Stem Cells Int. 2020 Mar 9;2020:4356359.
- Deola S, Cugno C, et al. Evidence for CD19B-CD8T Cell Interactions in Blood and Tissues from Patients with Graft-Versus-Host Disease. Bone Marrow Transplant 2016, Nov 7.